Despite variation in the real amount of CENP-A nucleosomes at centromeres among organisms, the features of CENP-A are conserved as well as the budding fungus homolog can recovery a depletion of mammalian CENP-A (Wieland et al

Despite variation in the real amount of CENP-A nucleosomes at centromeres among organisms, the features of CENP-A are conserved as well as the budding fungus homolog can recovery a depletion of mammalian CENP-A (Wieland et al., 2004;Karpen and Allshire, 2008).

Interestingly, in mut1- and mut2-expressing cells, nuclear accumulation of PY-STAT1 was only partially blocked, an observation that correlates with the attenuated phenotype observed in the reporter gene assay

Interestingly, in mut1- and mut2-expressing cells, nuclear accumulation of PY-STAT1 was only partially blocked, an observation that correlates with the attenuated phenotype observed in the reporter gene assay. humans and nonhuman primates, with human fatality rates of up to 90%