This is consistent with the concept that protein oxidative damage during aging is not dependent upon the relative amount of a specific protein. DISCUSSION A novel feature of this study is that it compared the age-related pattern of carbonylation of
The alkyne group of 11 is shifted compared with 5, thus there is no interaction with the iron and the carbon chain is rotated towards a hydrophobic pocket formed by A73 and H74
The alkyne group of 11 is shifted compared with 5, thus there is no interaction with the iron and the carbon chain is rotated towards a hydrophobic pocket formed by A73 and H74. IspH. Introduction Metalloproteins containing [Fe4S4] clusters carry